The content of placental protein 12 in decidua and fetal membranes is greater than in placenta

The content of placental protein 12 in decidua and fetal membranes is greater than in placenta
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蜕膜和胎膜中胎盘蛋白12的含量高于胎盘

DOI:
10.1111/j.1471-0528.1984.tb04744.x
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发表时间:
1984
期刊:
BJOG: An International Journal of Obstetrics & Gynaecology
影响因子:
--
通讯作者:
M. Seppälä
M. Seppälä
中科院分区:
--
文献类型:
--
作者:
E. Rutanen;R. Koistinen;T. Wahlström;H. Bohn;M. Seppälä

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概括。采用放射免疫分析、凝胶过滤和十二烷基硫酸钠聚丙烯酰胺凝胶电泳研究胎盘、蜕膜和胎膜中胎盘蛋白12(PP12)的含量和性质。组织取自 12 例妊娠早期,8 例正常足月分娩后,其中 7 例还对绒毛膜和羊膜进行了研究。蜕膜和胎膜中的 PP12 含量高于胎盘。 PP12 含量的蜕膜/胎盘比率范围为 2 至 1154(平均 193,SEM 66)。这些结果表明 PP12 是一种蜕膜蛋白而不是胎盘蛋白。
Summary. Radioimmunoassay, gel filtration and sodium dodecyl sulphate‐polyacrylamide gel electrophoresis were used to study the content and properties of placental protein 12 (PP12) in the placenta, decidua and fetal membranes. The tissues were obtained from early pregnancy in 12 cases, and after normal term delivery in eight cases in seven of which chorion and amnion laeve were also studied. There was more PP12 in decidua and fetal membranes than in placenta. The decidua/placenta ratio of PP12 content ranged from 2 to 1154 (mean 193, SEM 66). These results suggest that PP12 is a decidual rather than placental protein.