TMS of the occipital face area modulates cross-domain identity priming
TMS of the occipital face area modulates cross-domain identity priming
复制标题
DOI：
10.1007/s00429-018-1768-0
复制
发表时间：
2019-01-01
影响因子：
3.1
通讯作者：
Kovacs, Gyula
中科院分区：
文献类型：
--
作者：
Ambrus, Geza Gergely;Amado, Catarina;Kovacs, Gyula
越来越多的证据表明，右枕面部区域（rOFA）除了在早期面部特征加工中发挥作用外，其作用还扩展到更高水平的图像独立加工。最近的研究表明，这一区域的活动也可能受到语义信息的调节。为了测试OFA是否以功能相关的方式对语义信息敏感，我们实施了一种跨域的名称-面孔启动范式，结合状态依赖的经颅磁刺激，从而刺激优先促进由不太活跃的神经群体编码的属性的处理。我们的志愿者执行了一个熟悉度的决策任务的目标人脸图像前面的素数是同一个身份的名字（一致），一个不同的人的名字（不一致），或字符串XXXXX'（无素数）。刺激rOFA在目标刺激开始，我们观察到的不一致启动的行为劣势的消失，相比，顶点控制条件。在全等条件和非主条件下的性能保持不变。这一结果表明，rOFA中存在参与身份语义处理的神经群体，可能与扩展人脸网络中的其他节点相互作用。
Accumulating evidence suggests that besides its function in early facial feature processing, the role of the right occipital face area (rOFA) extends to higher level, image-independent processing. Recent studies hint at the possibility that the activity of this region can be modulated by semantic information as well. To test whether the OFA is sensitive to semantic information in a functionally relevant way, we implemented a cross-domain, name-face priming paradigm combined with state-dependent transcranial magnetic stimulation, whereby stimulation preferentially facilitates the processing of attributes encoded by less active neural populations. Our volunteers performed a familiarity decision task for target face images preceded by primes that were either the name of the same identity (congruent), a name of a different person (incongruent), or the character string XXXXX' (no prime). Stimulating the rOFA at target stimulus onset, we observed the disappearance of the behavioral disadvantage of incongruent primes, compared to the vertex control condition. Performance in the congruent and no prime conditions remained intact. This result suggests the existence of neural populations in the rOFA that take part in the semantic processing of identity, probably in interplay with other nodes in the extended face network.