Vitamin D supplementation effects on the clinical outcomes of patients with coronary artery disease: a systematic review and meta-analysis
Vitamin D supplementation effects on the clinical outcomes of patients with coronary artery disease: a systematic review and meta-analysis
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DOI：
10.1038/s41598-020-69762-w
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发表时间：
2020-07-31
影响因子：
4.6
通讯作者：
Arabi, Seyyed Mostafa
中科院分区：
文献类型：
--
作者：
Bahrami, Leila Sadat;Ranjbar, Golnaz;Arabi, Seyyed Mostafa
在这项系统性综述和荟萃分析中，我们的目的是评估补充维生素D对冠心病(CAD)患者心脏结局的影响。检索词为2000-01-2018-01，只考虑人类受试者的随机临床试验(RCT)，没有语言限制。本研究使用的电子数据库有：PubMed、Cochran图书馆、Embase和Scope。根据Cochrane的建议，两名独立专家审查员进行了数据提取。只有四项随机对照试验与补充维生素D对冠状动脉疾病的影响有关。在这299例患者中，补充维生素D对舒张压(DBP)(-2.96，p=0.02)和甲状旁腺激素(PTH)(-4.05，p=0.02)有显著的改善作用。
In this systematic review and meta-analysis our aim was to assess the effect of vitamin D supplementation on cardiac outcomes in patients with coronary artery disease (CAD). The search terms were performed from January 2000 to January 2018, only randomized clinical trials (RCT) in human subjects were considered, with no language restrictions. The electronic databases used in this study were: PubMed; Cochran library; Embase; and Scopus. Two independent expert reviewers carried out data extraction according to Cochrane recommendations. Only four RCTs were found in relation to the effects of vitamin D supplementation on the coronary artery disease. In these 299 patients, vitamin D supplementation had significant favorable effects on Diastolic Blood Pressure (DBP) (- 2.96, p=0.02) and Parathyroid hormone (PTH) (- 4.05, p