RECURRENT GENITOURINARY CHLAMYDIAL INFECTIONS IN SEXUALLY ACTIVE FEMALE ADOLESCENTS
RECURRENT GENITOURINARY CHLAMYDIAL INFECTIONS IN SEXUALLY ACTIVE FEMALE ADOLESCENTS
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DOI：
10.1016/s0022-3476(05)81812-8
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发表时间：
1992-09-01
影响因子：
5.1
通讯作者：
JONES, RB
中科院分区：
文献类型：
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作者：
BLYTHE, MJ;KATZ, BP;JONES, RB
为了确定衣原体感染的复发率，我们首先筛选了1308个性活跃的女性青少年在尿道和宫颈内的衣原体感染的城市人口，这些年轻女性进行了随访，并进行了额外的感染检查。在研究期间的某个时间，31.1%（407）的患者通过组织培养证实了衣原体感染。在适当的抗生素治疗后，68.3%（278/407）在初次感染后3个月内返回进行治愈测试培养;在这278例患者中，共有254例进行了无菌培养。对这些患者进行随访，以确定衣原体感染的复发率。在这254例患者中，177例（69.7%）接受了一次或多次随访; 38.4%（68/177）的患者有复发性衣原体感染。大多数复发性感染是在初次感染后9个月内记录的。相同血清型的复发感染是频繁的，这表明未经治疗的合作伙伴或可能复发的初始衣原体感染的再感染。如此高的复发率表明，女性青少年应经常重新筛查泌尿生殖道衣原体感染。
To determine the recurrence rate of chlamydial infections, we initially screened an urban population of 1308 sexually active female adolescents for chlamydial infection at the urethral and endocervical sites; these young women were followed and had additional examinations for infection. Chlamydial infection was documented by tissue culture in 31.1% (407) of them at some time during the study. After appropriate antibiotic treatment, 68.3% (278/407) returned for test-of-cure cultures within 3 months of their initial infection; of those 278, a total of 254 had sterile cultures. These patients were followed to determine the recurrence rate of chlamydial infections. Of these 254 patients, 177 (69.7%) had one or more follow-up visits; 38.4% (68/177) had a recurrent chlamydial infection. The majority of recurrent infections were documented within 9 months of the initial infection. Recurrent infections with the same serovar were frequent, suggesting reinfection by untreated partners or possible relapse of the initial chlamydial infection. This high rate of recurrent infection suggests that female adolescents should be rescreened frequently for genitourinary chlamydial infections.