Bone Quantitative Ultrasound: New Horizons
Bone Quantitative Ultrasound: New Horizons
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DOI：
10.1007/978-3-030-91979-5
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发表时间：
2022
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更好地了解儿童骨骼的力学行为对于改善可能影响骨骼发育的儿科骨骼疾病的诊断至关重要。尽管骨生长的过程被很好地描述，但仍然缺乏对儿童骨的内在材料特性的知识，特别是对被认为是“非病理性”的儿童骨的知识。几何形状、材料特性、微观结构和生化成分与儿童骨脆性相关，并且由于两个主要原因仍然难以评估：骨样本的稀缺性和它们的小尺寸。在这种情况下，超声波方法提供了有趣的可能性，特别是利用其非破坏性的特点。在本章中，非病理性儿童皮质骨（NPCCB）的弹性性能的超声方法获得。目的是促进建立一个关于全国预防犯罪和刑事案件的参考数据库，作为分析病理或治疗效果的比较点。在对NPCCB的弹性和各向异性的假设进行介绍之后，介绍了超声透射模式和共振光谱方法。结果提出和讨论相对于微观结构和生物化学性质。
A better understanding of the mechanical behaviour of child bone is essential to improve the diagnosis of pediatric bone disorders that may influence bone development. Even though the process of bone growth is well described, there are still lacks of knowledge on intrinsic material properties of child bone and particularly on child bone considered as “non-pathological”. Geometry, material properties, microstructure and biochemical components are associated with child bone fragility and remain difficult to assess for two main reasons: the scarcity of the bone samples and their small dimensions. In this context, ultrasonic methods offer interesting possibilities by exploiting in particular their non-destructive character. In this chapter, the elasticity properties of Non Pathological Child Cortical Bone (NPCCB) obtained by ultrasonic methods are presented. The objective was to contribute to the construction of a reference database on NPCCB that would serve as a point of comparison for analyzing the effect of a pathology or treatment. After the presentation of the hypotheses on the elasticity and anisotropy of NPCCB, ultrasonic transmission-mode and resonance spectroscopy methods are described. Results are presented and discussed with respect to microstructural and biochemical properties.