Leishmania Major Infection Among Psammomys Obesus and Meriones Shawi: Reservoirs of Zoonotic Cutaneous Leishmaniasis in Sidi Bouzid (Central Tunisia)
Leishmania Major Infection Among Psammomys Obesus and Meriones Shawi: Reservoirs of Zoonotic Cutaneous Leishmaniasis in Sidi Bouzid (Central Tunisia)
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DOI：
10.1089/vbz.2011.0712
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发表时间：
2011-12-01
影响因子：
2.1
通讯作者：
Ben-Salah, Afif
中科院分区：
文献类型：
--
作者：
Ghawar, Wissem;Toumi, Amine;Ben-Salah, Afif
2008年11月至2010年3月，在突尼斯中部皮肤利什曼病的重点进行了一项研究，以评估肥胖沙鼠（n = 472）和沙威沙鼠（n = 167）作为主要利什曼原虫感染的储存宿主的作用。L.的流行在肥胖丙酸杆菌和支原体中，培养的主要感染率分别为7%和5%（p =不显著[NS]），直接涂片检查的主要感染率分别为19%和16%（p = NS），间接荧光抗体试验的主要感染率分别为20%和33%（p = NS）。Shawi，分别。两种鼠的感染高峰均在冬季和秋季，并随年龄增长而逐渐增加。临床检查显示，脱毛、色素沉着过度、灼热和耳朵上缘严重水肿是研究样本中观察到的最常见体征（所有体征合并：肥胖猪为47%，M. shawi; p = NS）。然而，病变是双边的，似乎是更具破坏性的M。shawi与P. obesus进行了比较。两种啮齿类动物的无症状感染率均为40%。本研究表明M. Shawi在突尼斯的主要皮肤利什曼病的传播和出现中起着重要作用。
A study was undertaken between November 2008 and March 2010, in the focus of cutaneous leishmaniasis of Central Tunisia, to evaluate the role of Psammomys obesus (n = 472) and Meriones shawi (n = 167) as reservoir hosts for Leishmania major infection. Prevalence of L. major infection was 7% versus 5% for culture (p = not signifiant [NS]), 19% versus 16% for direct examination of smears (p = NS), and 20% versus 33% (p = NS) for Indirect Fluorescent Antibody Test among P. obesus and M. shawi, respectively. The peak of this infection was in winter and autumn and increased steadily with age for the both species of rodents. The clinical examination showed that depilation, hyper-pigmentation, ignition, and severe edema of the higher edge of the ears were the most frequent signs observed in the study sample (all signs combined: 47% for P. obesus versus 43% for M. shawi; p = NS). However, the lesions were bilateral and seem to be more destructive among M. shawi compared with P. obesus. Asymptomatic infection was similar to 40% for both rodents. This study demonstrated that M. shawi plays an important role in the transmission and the emergence of Leishmania major cutaneous leishmaniasis in Tunisia.