Norovirus highly prevalent cause of endemic acute diarrhea in children in the peruvian Amazon.
Norovirus highly prevalent cause of endemic acute diarrhea in children in the peruvian Amazon.
复制标题
诺如病毒是秘鲁亚马逊地区儿童地方性急性腹泻的高度流行原因。
DOI：
10.1097/inf.0b013e3181a24730
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Kosek,Margaret
中科院分区：
文献类型：
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作者：
Yori,PabloPenataro;Schwab,Kellogg;Gilman,RobertH;Nappier,Sharon;Portocarrero,DanielVelasquez;Black,RobertE;Olortegui,MaribelParedes;Hall,EricR;Moe,Christine;Leon,Juan;Cama,VitaA;Kosek,Margaret
为了确定诺沃克病毒在儿童粪便中的感染负担，采用逆转录聚合酶链式反应对纵向社区队列中的儿童粪便进行了评估。在腹泻性粪便中检出诺如病毒的比例为21.3%，在非腹泻性粪便中检出诺沃克病毒的比例为8.0%(P<；0.01)。诺如病毒腹泻与年龄高度相关，每月诺如病毒腹泻的优势比下降2.8%(OR=0.97，95%CI：0.95~0.99)。诺如病毒似乎是本研究人群中社区获得性腹泻的重要病原学。
To determine the burden of norovirus infections in children stools from a longitudinal community cohort were evaluated using reverse transcription polymerase chain reaction. Norovirus was detected in 21.3% of diarrheal and 8.0% of nondiarrheal stools (P< 0.01). Norovirus diarrhea was highly associated with age and the odds ratio for norovirus diarrhea fell by 2.8% per month (OR= 0.97, 95% CI: 0.95–0.99). Norovirus seems to be an important etiology of community acquired diarrhea in this study population.