The burden of prostate cancer in Asian nations.
The burden of prostate cancer in Asian nations.
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亚洲国家的前列腺癌负担。
DOI：
10.4103/1477-3163.94025
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发表时间：
2012
影响因子：
--
通讯作者：
McLeod DG
中科院分区：
文献类型：
--
作者：
Cullen J;Elsamanoudi S;Brassell SA;Chen Y;Colombo M;Srivastava A;McLeod DG
在这篇综述中，国际癌症研究机构的癌症流行病学数据库被用来检查前列腺癌（PCa）的年龄标准化发病率（ASIR）在选定的亚洲国家，包括癌症发病率在五大洲（CI 5）和GLOBOCAN数据库，在努力确定是否ASIR正在上升，在世界各地的前列腺癌发展的历史低风险地区。本次审查考虑了具有足够数据质量的亚洲国家。在四个符合条件的国家（中国、日本、韩国和新加坡）检查了CI 5和GLOBOCAN 2008公共使用数据库的PCa ASIR估计值。使用CI 5 AII-IX检查PCa ASIR的时间趋势。虽然PCa ASIR在所研究的亚洲国家中仍然比北美低得多，但在所研究的四个国家中，PCa ASIR有明显的增加趋势。必须扩大努力，系统地收集亚洲国家的癌症发病率数据。目前的CI 5数据表明，在几个人口众多的亚洲国家，PCa ASIR有所上升。如果这些比率继续上升，则不确定是否有足够的资源，即训练有素的人员和医疗基础设施以及连续护理，来处理PCa患者数量的增加。一些专家建议在亚洲国家启动PSA筛查，这可能会加剧资源短缺。获得这些国家PCa发病率的准确估计值对于准备应对这种疾病造成的公共卫生负担的潜在转变至关重要。
In this review, the International Agency for Research on Cancer's cancer epidemiology databases were used to examine prostate cancer (PCa) age-standardized incidence rates (ASIR) in selected Asian nations, including Cancer Incidence in Five Continents (CI5) and GLOBOCAN databases, in an effort to determine whether ASIRs are rising in regions of the world with historically low risk of PCa development. Asian nations with adequate data quality were considered for this review. PCa ASIR estimates from CI5 and GLOBOCAN 2008 public use databases were examined in the four eligible countries: China, Japan, Korea and Singapore. Time trends in PCa ASIRs were examined using CI5 Volumes I-IX. While PCa ASIRs remain much lower in the Asian nations examined than in North America, there is a clear trend of increasing PCa ASIRs in the four countries examined. Efforts to systematically collect cancer incidence data in Asian nations must be expanded. Current CI5 data indicate a rise in PCa ASIR in several populous Asian countries. If these rates continue to rise, it is uncertain whether there will be sufficient resources in place, in terms of trained personnel and infrastructure for medical treatment and continuum of care, to handle the increase in PCa patient volume. The recommendation by some experts to initiate PSA screening in Asian nations could compound a resource shortfall. Obtaining accurate estimates of PCa incidence in these countries is critically important for preparing for a potential shift in the public health burden posed by this disease.