WormBase 2016: expanding to enable helminth genomic research.

WormBase 2016: expanding to enable helminth genomic research.
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DOI:
10.1093/nar/gkv1217
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发表时间:
2016-01-04
影响因子:
14.9
通讯作者:
Sternberg PW
Sternberg PW
中科院分区:
生物学2区
文献类型:
--
作者:
Howe KL;Bolt BJ;Cain S;Chan J;Chen WJ;Davis P;Done J;Down T;Gao S;Grove C;Harris TW;Kishore R;Lee R;Lomax J;Li Y;Muller HM;Nakamura C;Nuin P;Paulini M;Raciti D;Schindelman G;Stanley E;Tuli MA;Van Auken K;Wang D;Wang X;Williams G;Wright A;Yook K;Berriman M;Kersey P;Schedl T;Stein L;Sternberg PW

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WormBase(www.wormbase.org)是一个关于秀丽隐杆线虫和其他线虫的生物学、遗传学和基因组学研究数据的中央储存库。该项目已经从最初的收集和整合单个物种的所有数据的职责,现在扩展到许多线虫,从C。从线虫到威胁植物、动物和人类健康的寄生物种。使用C. elegans作为一个模型系统一如既往地充满活力,我们已经为社区管理创建了新的工具,以应对不断增加的数据量和复杂性。为了更好地让用户浏览这些数据,我们对我们的主网站进行了一些改进,包括用于浏览基因组特征和本体注释的新工具。最后,我们开发了一个新的寄生虫基因组门户网站。WormBase ParaSite(parasite.wormbase.org)包含所有公开可用的线虫和扁形蠕虫注释基因组序列,专门用于支持蠕虫基因组研究。
WormBase (www.wormbase.org) is a central repository for research data on the biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The project has evolved from its original remit to collect and integrate all data for a single species, and now extends to numerous nematodes, ranging from evolutionary comparators of C. elegans to parasitic species that threaten plant, animal and human health. Research activity using C. elegans as a model system is as vibrant as ever, and we have created new tools for community curation in response to the ever-increasing volume and complexity of data. To better allow users to navigate their way through these data, we have made a number of improvements to our main website, including new tools for browsing genomic features and ontology annotations. Finally, we have developed a new portal for parasitic worm genomes. WormBase ParaSite (parasite.wormbase.org) contains all publicly available nematode and platyhelminth annotated genome sequences, and is designed specifically to support helminth genomic research.