Determination of total purine and purine base content of 80 food products to aid nutritional therapy for gout and hyperuricemia

Determination of total purine and purine base content of 80 food products to aid nutritional therapy for gout and hyperuricemia
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DOI:
10.1080/15257770.2020.1748197
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发表时间:
2020-04-07
影响因子:
1.3
通讯作者:
Fujimori, Shin
Fujimori, Shin
中科院分区:
生物学4区
文献类型:
--
作者:
Kaneko, Kiyoko;Takayanagi, Fukue;Fujimori, Shin

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这项工作的目的是促进痛风和高尿酸血症的营养治疗。在日本,痛风或高尿酸血症患者建议每天摄入的膳食嘌呤含量低于 400 毫克。当接受痛风或高尿酸血症的营养治疗时,富含嘌呤的食物(>200毫克/100克)应该减少食用量。本研究报告的食物嘌呤含量如下:面条,0.6-12.1mg/100g;面包,4.4 毫克/100 克;豌豆或种子,19.6-67.1 毫克/100 克;乳制品,0.0-1.4 毫克/100 克;日本蔬菜,0.9-47.1毫克/100克;调味料,0.7-847.1毫克/100克;肉或鱼,19.0-385.4 毫克/100 克;鱼精,375.4-559.8 毫克/100 克;和补充剂,81.9-516.0 毫克/100 克。含有大量嘌呤(>300毫克/100克)的食物包括凤尾鱼、带鱼、鳕鱼白、河豚鱼白、干汤料、干酵母、眼虫补充剂和乳酸菌补充剂。食用这些高嘌呤食物或补充剂时,一餐的摄入量应受到限制,尤其是精米,因为它们通常摄入的量为20-30克,相当于75-168毫克总嘌呤。这是痛风或高尿酸血症患者推荐每日用量(400 毫克/天)的 20%-40%。因此,这些患者应该限制富含嘌呤食物的摄入量。建议保持良好的营养平衡的饮食习惯。
The aim of this work is to facilitate the nutritional therapy of gout and hyperuricemia. In Japan, patients with gout or hyperuricemia are recommended to consume less than 400 mg of dietary purines per day. When receiving nutritional therapy for gout or hyperuricemia, purine-rich foods (>200 mg/100 g) should be eaten in even lower quantities. The purine content of foods reported in this study are as follows: noodles, 0.6-12.1 mg/100 g; bread, 4.4 mg/100 g; peas or seeds, 19.6-67.1 mg/100 g; dairy, 0.0-1.4 mg/100 g; Japanese vegetables, 0.9-47.1 mg/100 g; seasonings, 0.7-847.1 mg/100 g; meat or fish, 19.0-385.4 mg/100 g; fish milt, 375.4-559.8 mg/100 g; and supplements, 81.9-516.0 mg/100 g. Foods containing very large amounts of purine (>300 mg/100 g) included anchovy, cutlassfish (hairtail), cod milt, globefish milt, dried Chinese soup stock, dried yeast, a Euglena supplement, and a Lactobacillus supplement. When eating these high-purine food or supplements, the quantity taken at one meal should be limited, especially milt because they typically consumed amount of 20-30 g is equivalent to 75-168 mg total purines. This is 20%-40% of the recommended daily amount (400 mg/day) for patients with gout or hyperuricemia. Thus, these patients should restrict the amount of purine-rich foods they consume. Good dietary habits with a good balance of nutrients are recommended.