BIOSTATISTICAL ANALYSIS OF THE COLLABORATIVE GLAUCOMA STUDY .1. SUMMARY REPORT OF THE RISK-FACTORS FOR GLAUCOMATOUS VISUAL-FIELD DEFECTS
BIOSTATISTICAL ANALYSIS OF THE COLLABORATIVE GLAUCOMA STUDY .1. SUMMARY REPORT OF THE RISK-FACTORS FOR GLAUCOMATOUS VISUAL-FIELD DEFECTS
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DOI：
10.1001/archopht.1980.01020041015002
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发表时间：
1980-01-01
影响因子：
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通讯作者：
SHAFFER, RN
中科院分区：
文献类型：
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作者：
ARMALY, MF;KRUEGER, DE;SHAFFER, RN
在5个中心对影响开角型青光眼患者视野缺损（GVFD）发展的因素进行了为期13年的研究。在5000例受试者中，仅1.7%的眼睛发生GVFD。对第一次检查的26个因素进行统计分析，发现5个因素与GVFD的发生显著相关：流出道设施、年龄、压平压力、杯盘比和饮水后压力变化。它们的绝对初始值，而不是它随时间的变化，是重要的预测因子。多变量分析表明，他们的集体预测能力是不可取的穷人，表明其他因素必须发挥重要作用的发展GVFD。死亡率表分析表明，在5年内，98.54%的眼初始压力小于20毫米汞柱的无GVFD相比，93.34%的那些压力20毫米汞柱或更高。
In 5 centers, factors influencing the development of visual-field defects (GVFD) in open-angle glaucoma patients were studied for 13 yr. In 5000 subjects, GVFD developed in only 1.7% of eyes. Statistical analysis of 26 factors at 1st examination identified 5 significantly related to the development of GVFD: outflow facility, age, applanation pressure, cup-disc ratio and pressure change after water drinking. Their absolute initial value, and not its change with time, was the important predictor. Multivariate analysis showed their collective predictive power to be undesirably poor indicating that other factors must play an important role in the development of GVFD. Mortality-table analysis indicated that during 5 yr, 98.54% of eyes with initial pressure less than 20 mm Hg were free from GVFD as compared with 93.34% of those with pressure 20 mm Hg or greater.