An event-related functional magnetic resonance imaging study of voluntary and stimulus-driven orienting of attention
An event-related functional magnetic resonance imaging study of voluntary and stimulus-driven orienting of attention
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DOI：
10.1523/jneurosci.0236-05.2005
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发表时间：
2005-05-04
影响因子：
5.3
通讯作者：
Corbetta, M
中科院分区：
文献类型：
--
作者：
Kincade, JM;Abrams, RA;Corbetta, M
注意力可以被自发地引导到一个位置，也可以被显著的刺激自动地召唤到一个位置。我们比较了自发性和刺激驱动的空间注意力转移对人类血氧水平依赖信号的影响，采用了一种方法，将与初始注意力转移相关的准备活动与目标呈现引起的后续活动分开。在额顶叶背侧注意网络的核心区域额视野（FEF）和顶叶内沟，自愿性转移比刺激驱动的转移产生了更大的准备活动，证明了它们在注意的自愿性控制中的特殊作用。刺激驱动的注意力转移到显著颜色单色的过程涉及对颜色信息敏感的枕颞区和部分背侧网络，包括FEF，这表明内源性和外源性定向有部分重叠的回路。右颞顶叶交界处（TPJ）是腹侧额顶叶注意网络的核心区域，刺激驱动的注意转移对行为相关刺激（如无人注意位置的目标）具有强烈的调节作用。然而，TPJ并没有对显著的、与任务无关的颜色单色做出反应，这表明在刺激驱动定向过程中，行为相关性对TPJ调节至关重要。最后，腹侧和背侧区域在重新定向过程中都被调节，但只有在自愿移位后重新定向时才会被显著调节，这表明期望和感觉输入之间不匹配的重要性。
Attention can be voluntarily directed to a location or automatically summoned to a location by a salient stimulus. We compared the effects of voluntary and stimulus-driven shifts of spatial attention on the blood oxygenation level-dependent signal in humans, using a method that separated preparatory activity related to the initial shift of attention from the subsequent activity caused by target presentation. Voluntary shifts produced greater preparatory activity than stimulus-driven shifts in the frontal eye field (FEF) and intraparietal sulcus, core regions of the dorsal frontoparietal attention network, demonstrating their special role in the voluntary control of attention. Stimulus-driven attentional shifts to salient color singletons recruited occipitotemporal regions, sensitive to color information and part of the dorsal network, including the FEF, suggesting a partly overlapping circuit for endogenous and exogenous orienting.The right temporoparietal junction (TPJ), a core region of the ventral frontoparietal attention network, was strongly modulated by stimulus-driven attentional shifts to behaviorally relevant stimuli, such as targets at unattended locations. However, the TPJ did not respond to salient, task-irrelevant color singletons, indicating that behavioral relevance is critical for TPJ modulation during stimulus-driven orienting. Finally, both ventral and dorsal regions were modulated during reorienting but significantly only by reorienting after voluntary shifts, suggesting the importance of a mismatch between expectation and sensory input.