Autoimmune markers and autoimmune disorders in patients with postural tachycardia syndrome (POTS)
Autoimmune markers and autoimmune disorders in patients with postural tachycardia syndrome (POTS)
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DOI：
10.1177/0961203315587566
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发表时间：
2015-11-01
期刊：
影响因子：
2.6
通讯作者：
Blitshteyn, S.
中科院分区：
文献类型：
--
作者：
Blitshteyn, S.
目的近年来，大量研究提示POTS可能存在自身免疫性病因。本研究探讨是否抗核抗体（ANA），自身免疫和共病自身免疫性疾病的其他标志物的患病率较高的POTS患者比在一般population.Methods和结果的100例连续POTS患者的病历进行了评估，在我们的诊所进行了审查。在该队列中（90%女性，平均年龄32岁，范围13-54岁），25% ANA阳性，7%至少有一种aPL抗体阳性，31%有自身免疫标志物。与普通人群相比，POTS患者的ANA患病率更高（25% vs. 16%，OR 1.8，CI 1.1-2.8，p
Objective In recent years, there have been a number of studies suggesting that POTS may have an autoimmune etiology. This study examined whether the prevalence of antinuclear antibodies (ANA), other markers of autoimmunity and co-morbid autoimmune disorders is higher in patients with POTS than in the general population.Methods and results Medical records of 100 consecutive patients with POTS evaluated at our clinic were reviewed. In this cohort (90% females, mean age 32, range 13-54 years), 25% had positive ANA, 7% had at least one positive aPL antibody and 31% had markers of autoimmunity. When compared to the general population, patients with POTS had a higher prevalence of ANA (25% vs. 16%, OR 1.8, CI 1.1-2.8, p