A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging
A longitudinal study of brain volume changes in normal aging using serial registered magnetic resonance imaging
复制标题
DOI：
10.1001/archneur.60.7.989
复制
发表时间：
2003-07-01
影响因子：
--
通讯作者：
Fox, NC
中科院分区：
文献类型：
--
作者：
Scahill, RI;Frost, C;Fox, NC
目的：探讨年龄对整体和局部脑容量及脑萎缩率的影响，并比较基于横断面和纵向数据的直接结果。方法：39例健康对照者（年龄31-84岁）进行了连续磁共振成像评估。测量包括基线和重复扫描时的全脑、颞叶、海马和心室容积。结果：我们发现全脑横切面(P
Objective: To investigate the effect of age on global and regional brain volumes and rates of atrophy, and to compare directly results based on cross-sectional and longitudinal data.Methods: Thirty-nine healthy control subjects (age range, 31-84 years) underwent serial magnetic resonance imaging assessments. Measurements included the whole-brain, temporal lobe, hippocampal, and ventricular volumes at baseline and for repeat scans.Results: We found significant decreases in cross-sectional whole-brain (P