Unilateral recalcitrant glaucoma associated with cytomegalovirus in an immunocompromised child with Wiskott-Aldrich syndrome

Unilateral recalcitrant glaucoma associated with cytomegalovirus in an immunocompromised child with Wiskott-Aldrich syndrome
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DOI:
10.1016/j.jaapos.2013.08.007
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发表时间:
2013-12-01
期刊:
影响因子:
1.6
通讯作者:
Pandav, Surinder Singh
Pandav, Surinder Singh
中科院分区:
医学4区
文献类型:
--
作者:
Kaushik, Sushmita;Singh, Ramandeep;Pandav, Surinder Singh

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我们报道了一名患有前葡萄膜炎和单侧顽固性青光眼的病例,该病例是一名免疫功能低下的 6 岁男孩,被诊断为 Wiskott-Aldrich 综合征,表现为眼压 (IOP) 升高、轻度前葡萄膜炎和单侧急性青光眼。水溶液的聚合酶链反应呈巨细胞病毒 (CM) 阳性。最初对更昔洛韦有反应后,眼压再次上升。随着视神经状态恶化,患者接受了丝裂霉素 C 青光眼滤过手术,并开始了 CMV 视网膜炎术后治疗方案。
We report a case of anterior uveitis and unilateral recalcitrant glaucoma in an immunocompromised 6-year-old boy diagnosed with Wiskott-Aldrich syndrome who presented with elevated intraocular pressure (IOP), mild anterior uveitis, and unilateral acute glaucoma. Polymerase chain reaction from the aqueous was positive for cytomegalovirus (CM). After initially responding to ganciclovir, the IOP rose again. With worsening optic nerve status, the patient underwent glaucoma filtration surgery with mitomycin C, and a postoperative regimen for CMV retinitis was initiated.