Neural Modulation by Binocular Disparity Greatest in Human Dorsal Visual Stream
Neural Modulation by Binocular Disparity Greatest in Human Dorsal Visual Stream
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DOI：
10.1152/jn.00790.2009
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发表时间：
2010-07-01
影响因子：
2.5
通讯作者：
Bridge, Holly
中科院分区：
文献类型：
--
作者：
Minini, Loredana;Parker, Andrew J.;Bridge, Holly
L，帕克，布里奇·H。双眼视差对神经的调制在人的背侧视流中最大。《神经生理学杂志》104：169-178,2010。2010年5月5日首次出版；DOI：10.1152/jn.00790.2009。虽然大脑皮质对双眼视差的激活可以在整个枕叶和顶叶皮质得到证实，但人类不同皮质区域对深度知觉的相对贡献尚未确定。为了研究不同区域是否对特定的视差范围进行了优化，我们测量了枕区和顶区对不同程度的双眼视差的反应。使用由正弦深度调制组成的刺激，我们测量了当刺激位于距注视的基座差为0、0.1、0.35和0.7时的皮质激活。在所有区域，枕骨和顶骨，与零视差平面相比，随着基座差异的增加，大胆信号增加。但是，不同基座对反应的调制作用最大的是背侧视区和顶区。这些差异与对零视差面的反应形成对比，与凝视相比，凝视在早期视觉区域最大，在腹侧和背侧视觉区域较小，在顶区没有。使用同时获得的心理物理数据，我们还测量了对正确试验的反应比对不正确试验的反应更大，这种反应随着底座差异的增加而增加，在背侧视觉和顶区最大。这些结果表明，沿着枕支和顶支的背侧流可以可靠地区分大范围的差异。
Minini L, Parker AJ, Bridge H. Neural modulation by binocular disparity greatest in human dorsal visual stream. J Neurophysiol 104: 169-178, 2010. First published May 5, 2010; doi:10.1152/jn.00790.2009. Although cortical activation to binocular disparity can be demonstrated throughout occipital and parietal cortices, the relative contributions to depth perception made by different human cortical areas have not been established. To investigate whether different regions are optimized for specific disparity ranges, we have measured the responses of occipital and parietal areas to different magnitudes of binocular disparity. Using stimuli consisting of sinusoidal depth modulations, we measured cortical activation when the stimuli were located at pedestal disparities of 0, 0.1, 0.35, and 0.7 from fixation. Across all areas, occipital and parietal, there was an increase in BOLD signal with increasing pedestal disparity, compared with a plane at zero disparity. However, the greatest modulation of response by the different pedestals was found in the dorsal visual areas and the parietal areas. These differences contrast with the response to the zero disparity plane, compared with fixation, which is greatest in the early visual areas, smaller in the ventral and dorsal visual areas, and absent in parietal areas. Using the simultaneously acquired psychophysical data we also measured a greater response to correct than to incorrect trials, an effect that increased with rising pedestal disparity and was greatest in dorsal visual and parietal areas. These results illustrate that the dorsal stream, along both its occipital and parietal branches, can reliably discriminate a large range of disparities.