Role of endogenous dopamine in the natriuresis accompanying various sodium challenges.
Role of endogenous dopamine in the natriuresis accompanying various sodium challenges.
复制标题
内源性多巴胺在伴随各种钠挑战的尿钠排泄中的作用。
DOI：
10.1093/ajh/3.6.90s
复制
发表时间：
1990
影响因子：
3.2
通讯作者：
Murphy,MB
中科院分区：
文献类型：
--
作者：
Bass,AS;Murphy,MB
本文综述了内源性多巴胺（DA）在各种钠刺激引起的钠尿中的作用。数据显示，DA参与控制正常钠饮食、钠消耗增加和急性等渗盐水输注所产生的钠排泄。相反，狗的钠尿伴随着高钠饮食和低渗盐水或大量等渗盐水的细胞外液容量扩张，与DA活性无关。因此，有证据表明，DA有助于某些（但不是全部）形式的钠负荷产生的尿钠。Am J Hypertens 1990；3:90s - 92 s
The contribution of endogenous dopamine (DA) to the natriuresis accompanying various sodium challenges is reviewed. Data are presented suggesting that DA participates in the control of sodium excre tion produced by a normal sodium diet, increments in sodium consumption, and an acute infusion of isoosmotic saline. In contrast, the natriuresis accompanying a high sodium diet in the dog and extracellular fluid volume expansion with hypoosmotic saline or a very large volume of isoosmotic saline is independent of DA activity. Thus, the evidence suggests that DA contributes to the natriuresis produced by some, but not all, forms of sodium loading. Am J Hypertens 1990;3:90S-92S