A QUANTITATIVE STUDY OF INTERMEDIOLATERAL COLUMN CELLS IN MOTOR NEURON DISEASE AND THE SHY-DRAGER SYNDROME

A QUANTITATIVE STUDY OF INTERMEDIOLATERAL COLUMN CELLS IN MOTOR NEURON DISEASE AND THE SHY-DRAGER SYNDROME
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DOI:
10.1136/jnnp.48.11.1103
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发表时间:
1985-01-01
影响因子:
11
通讯作者:
DUCHEN, LW
DUCHEN, LW
中科院分区:
医学1区
文献类型:
--
作者:
KENNEDY, PGE;DUCHEN, LW

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对 5 名死于运动神经元疾病、2 名死于 Shy-Drager 综合征和 3 名不影响脊髓或神经根的其他神经系统疾病的患者的胸脊髓灰质侧角的中间外侧柱神经元进行了计数。与对照索相比,所有运动神经元疾病病例中的中间外侧柱细胞数量略有减少,当评估整个胸交感神经流出及其上、中和下三分之一时,这种差异都很明显。然而,差异并不具有统计学意义。相比之下,在 Shy-Drager 病例中,与正常脊髓相比,中间外侧柱细胞显着减少。
The intermediolateral column neurons in the lateral horns of the grey matter of the thoracic spinal cord were counted in five patients who had died of motor neuron disease, two of the Shy-Drager syndrome and three of other neurological diseases not affecting the spinal cord or roots. The number of intermediolateral column cells in all the motor neuron disease cases was slightly reduced compared with the control cords, this difference being apparent both when the whole thoracic sympathetic outflow was assessed as well as its upper, middle and lower thirds. The difference, however, was not statistically significant. By contrast, in Shy-Drager cases there was a highly significant reduction in intermediolateral column cells compared with the normal cords.