CAPNOCYTOPHAGA BACTEREMIA IN A PATIENT WITH HODGKINS-DISEASE FOLLOWING BONE-MARROW TRANSPLANTATION - CASE-REPORT AND REVIEW
CAPNOCYTOPHAGA BACTEREMIA IN A PATIENT WITH HODGKINS-DISEASE FOLLOWING BONE-MARROW TRANSPLANTATION - CASE-REPORT AND REVIEW
复制标题
DOI：
10.1093/clinids/14.5.1045
复制
发表时间：
1992-05-01
影响因子：
11.8
通讯作者：
ASCENSAO, JL
中科院分区：
文献类型：
--
作者：
BILGRAMI, S;BERGSTROM, SK;ASCENSAO, JL
二氧化碳嗜纤维菌属是一种革兰氏阴性、嗜二氧化碳、兼性厌氧杆菌，通常栖息在口腔中。我们报告的情况下，病人谁开发二氧化碳噬纤维菌菌血症自体骨髓移植后霍奇金病，我们审查其他报告的情况下，二氧化碳噬纤维菌菌血症免疫功能低下的患者。在我们的病例中，移植前预处理后发生感染，并伴有严重的口腔粘膜炎和中性粒细胞减少症。抗生素治疗导致感染的临床解决。二氧化碳噬纤维菌血症应纳入免疫功能低下患者发热性中性粒细胞减少症的鉴别诊断（例如，接受骨髓移植的患者），尤其是在存在粘膜炎和牙龈出血的情况下。
Capnocytophaga is a gram-negative, capnophilic, facultatively anaerobic bacillus that normally inhabits the oral cavity. We report the case of a patient who developed capnocytophaga bacteremia following autologous bone marrow transplantation for Hodgkin's disease, and we review other reported cases of capnocytophaga bacteremia in immunocompromised patients. In our case infection followed pretransplantation conditioning and was associated with severe oral mucositis and neutropenia. Antibiotic therapy resulted in clinical resolution of infection. Capnocytophaga bacteremia should be included in the differential diagnosis of febrile neutropenia in immunocompromised patients (e.g., those undergoing bone marrow transplantation) especially in the presence of mucositis and gingival bleeding.