Interaction of tea catechins with lipid bilayers investigated with liposome systems
Interaction of tea catechins with lipid bilayers investigated with liposome systems
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DOI：
10.1271/bbb.63.2252
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发表时间：
1999-12-01
影响因子：
1.6
通讯作者：
Nakayama, T
中科院分区：
文献类型：
--
作者：
Hashimoto, T;Kumazawa, S;Nakayama, T
用脂质体系统研究了茶儿茶素与脂质双分子层的相互作用，使我们能够通过离心分离脂质体。我们发现表儿茶素没食子酸酯对脂质双分子层的亲和力最高，其次是没食子儿茶素没食子酸酯、表儿茶素和没食子儿茶素。表儿茶素没食子酸酯和表没食子儿茶素没食子酸酯在脂质双分子层表面扰乱了膜结构。
Interaction of tea catechins with lipid bilayers was investigated with liposome systems, which enabled us to separate liposomes from the external medium by centrifugation. we found that epicatechin gallate had the highest affinity for lipid bilayers, followed by epigallocatechin gallate, epicatechin, and epigallocatechin. Epicatechin gallate and epigallocatechin gallate in the surface of lipid bilayer perturbed the membrane structure.