Chemotherapy and targeted molecular therapies for brain metastases.
Chemotherapy and targeted molecular therapies for brain metastases.
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DOI：
10.1586/14737175.6.10.1465
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发表时间：
2006-10-01
影响因子：
4.3
通讯作者：
Wen, Patrick Y
中科院分区：
文献类型：
--
作者：
Drappatz, Jan;Wen, Patrick Y
随着全身性癌症治疗的改善，越来越多的患者发生脑转移。虽然传统的手术治疗、放射治疗和放射外科治疗已经改善了大量患者的预后，但许多患者出现了不适合标准治疗的多发性病变。本文就目前脑转移瘤的化疗和靶向分子药物的作用进行了综述，并对未来的研究方向进行了讨论。
As therapy for systemic cancers improves, an increasing number of patients are developing brain metastases. Although conventional therapy with surgery, radiation therapy and radiosurgery has improved the outcome of a significant number of patients, many develop multiple lesions that are not amenable to standard treatments. In this review, the current role of chemotherapy and targeted molecular agents for brain metastases is summarized and future directions are discussed.