Design and implementation of a high-throughput biological sample processing facility using modern manufacturing principles
Design and implementation of a high-throughput biological sample processing facility using modern manufacturing principles
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DOI：
10.1093/ije/dyn031
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发表时间：
2008-04-01
影响因子：
7.7
通讯作者：
Peakman, Tim C.
中科院分区：
文献类型：
--
作者：
Downey, Paul;Peakman, Tim C.
英国生物样本库是一项前瞻性研究，收集了50万志愿者参与者在4年内的生物样本和健康及生活方式数据。方法采用现代制造技术指导样品处理设备和自动化系统的开发，并对样品处理设备的技术、系统、专用工艺、自动化系统的设计和实现进行了分析和探讨。基础设施和适当的工作人员结构已经落实，这将提供和维持一种资源，英国生物库研究的长期目标。结论现代制造原理适用于高通量生物样品处理设施的开发。
Background UK Biobank is a prospective study that is collecting biological samples and health and lifestyle data from 500000 volunteer participants over a 4-year period. These data will be used to facilitate biological and medical research.Methods Modem manufacturing principles were used to direct the development of the sample processing facility and automated systems.Results A fit for purpose facility comprising technology, systems, dedicated process, infrastructure and an appropriate staff structure has been implemented that will deliver and maintain a resource that will support the long-term goals of the UK Biobank study.Conclusions Modern manufacturing principles are appropriate for use in the development of a high throughput biological sample processing facility.