Acoustophoresis separation method
Acoustophoresis separation method
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DOI：
10.1121/1.406934
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发表时间：
1993-03
影响因子：
2.4
通讯作者：
J. Heyman
中科院分区：
文献类型：
--
作者：
J. Heyman
本发明提供了一种用于声波电泳的方法和设备，即通过声波分离物质。一种超声波换能器将声波施加到含有至少两种具有不同声吸收的物质的样品容器的一端。波有一个频率调谐到或与将要分离的物种的共振点协调。这种波导致物种被驱赶到样品容器的另一端进行移除。可以提供第二超声波换能器以施加第二相反方向的声波以防止不希望的流。此外，调谐到机械共振并与磁场耦合的无线电频率可用于识别包含具有相似吸收系数的物种的介质中的物种，从而可以应用具有与该旋转速率对应的频率的声波将所识别的物种扫至容器的一端以去除。
A method and apparatus are provided for acoustophoresis, i.e., the separation of species via acoustic waves. An ultrasonic transducer applies an acoustic wave to one end of a sample container containing at least two species having different acoustic absorptions. The wave has a frequency tuned to or harmonized with the point of resonance of the species to be separated. This wave causes the species to be driven to an opposite end of the sample container for removal. A second ultrasonic transducer may be provided to apply a second, oppositely directed acoustic wave to prevent undesired streaming. In addition, a radio frequency tuned to the mechanical resonance and coupled with a magnetic field can serve to identify a species in a medium comprising species with similar absorption coefficients, whereby an acoustic wave having a frequency corresponding to this gyrational rate can then be applied to sweep the identified species to one end of the container for removal.