Update on Chagas' disease in Mexico.

Update on Chagas' disease in Mexico.
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墨西哥恰加斯病的最新情况。

DOI:
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发表时间:
1999
期刊:
Salud Pública de México
影响因子:
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通讯作者:
Eric Dumonteil
Eric Dumonteil
中科院分区:
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文献类型:
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作者:
Eric Dumonteil

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由原生动物寄生虫克氏锥虫引起的恰加斯病是美洲大陆大部分地区的一个主要公共卫生问题。由于南美洲大部分地区的寄生虫传播已被阻断,该疾病在墨西哥各地区仍是地方病。我们在此回顾近年来收集的一些信息。T.在一些地区,人类的克氏克鲁济感染率仍然较高,近年来向卫生当局报告的慢性病例数量普遍增加。事实上,慢性心肌病似乎影响了大量的心脏病患者,但由于临床症状的不特异性,许多病例可能被误报。对病媒和水库种群以及人间病例的流行病学监测有助于把重点放在流行地区,但仍需更好地协调和发展这些努力。最近的寄生虫生物学研究与以前的工作一致,显示了寄生虫特征的巨大多样性,并支持需要对这种人畜共患病采取区域性方法。因此,仍然需要卫生和学术当局的强有力和持续支持,以进一步提高我们对墨西哥恰加斯病的了解并实施有效的控制计划。
Chagas' disease, caused by the protozoan parasite Trypanosoma cruzi, represents a major public health problem in most of the American continent. As transmission of the parasite is being interrupted in most of South America, the disease remains endemic in various areas of Mexico. We review here some of the information gathered in recent years. Seroprevalence of T. cruzi infection in humans remains relatively high in some areas, and there has been a general increase in the number of chronic cases reported to health authorities in recent years. In fact, chronic chagasic cardiomyopathy appears to be affecting a large number of patients with heart disease, but many cases may be misreported because of the unspecific nature of the clinical symptoms. Epidemiological monitoring of vector and reservoir populations, as well as of human cases is helping focus on endemic areas, but a better coordination and development of these efforts is still needed. Recent studies of parasite biology are in agreement with previous work showing the great diversity of parasite characteristics, and support the need for a regional approach to this zoonosis. Strong and continuing support from health and academic authorities is thus still needed to further improve our understanding of Chagas' disease in Mexico and implement efficient control programs.
DOI: 10.1021/jm970860z
发表时间: 1998-04-23
影响因子: 7.3
作者:
Cinque, GM;Szajnman, SH;Gros, EG
通讯作者: Gros, EG