Relation between Parametric Change of the Workload and Prefrontal Cortex Activity during a Modified Version of the ‘Rock, Paper, Scissors' Task
Relation between Parametric Change of the Workload and Prefrontal Cortex Activity during a Modified Version of the ‘Rock, Paper, Scissors' Task
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DOI：
10.1159/000350948
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发表时间：
2013-06
影响因子：
3.2
通讯作者：
Y. Yamauchi;Senichiro Kikuchi;F. Miwakeichi;Kenji Matsumoto;M. Nishida;M. Ishiguro;Eiju Watanabe;S. Kato
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文献类型：
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作者：
Y. Yamauchi;Senichiro Kikuchi;F. Miwakeichi;Kenji Matsumoto;M. Nishida;M. Ishiguro;Eiju Watanabe;S. Kato
背景/目标：修改的石头，布，剪刀（RPS）任务以前曾被用于神经科学研究前额叶皮层（PFC）的活动。在这项研究中，我们研究了血流动力学的变化，在PFC使用近红外光谱（NIRS）在一个修改后的RPS任务，其中每个主题的成功执行率是均衡的，工作量增加参数，以揭示由此产生的模式PFC激活。方法：20例健康成人。在RPS中，玩家使用手势来代表石头、布和剪刀。石头赢剪刀，布赢石头，剪刀赢布。在修改后的RPS任务中，玩家被指示故意输给电脑手;电脑先走，玩家跟着。刺激间期（ISI）水平调整为11步。如果水平上升，ISI下降，工作量增加参数。最大水平（maxLv：最短ISI和最大工作量），其中受试者可以正确地执行该任务。降低maxLv的水平使任务变得更容易。采用近红外光谱仪（NIRS）测定4个任务水平（maxLv-3、maxLv-2、maxLv-1和maxLv）下的血流动力学变化。结果如下：左侧PFC和双侧Brodmann 6区血流动力学变化随负荷增加而显著升高，并呈线性趋势。结论：这些结果表明，PFC激活可能会线性增加，在一个修改后的RPS任务，其中成功的性能率的科目是均衡的工作量增加。
Background/Aims: Modified rock, paper, scissors (RPS) tasks have previously been used in neuroscience to investigate activity of the prefrontal cortex (PFC). In this study, we investigated hemodynamic changes in the PFC using near-infrared spectroscopy (NIRS) during a modified RPS task in which each subject's successful performance rate was equalized; the workload was increased parametrically in order to reveal the resulting pattern of PFC activation. Methods: The subjects were 20 healthy adults. During RPS, the player uses hand gestures to represent rock, paper, and scissors. Rock beats scissors, paper beats rock, and scissors beats paper. In the modified RPS task, the player is instructed to lose intentionally against the computer hand; the computer goes first and the player follows. The interstimulus interval (ISI) level was adjusted with 11 steps. If the level rose, the ISI decreased and the workload increased parametrically. The maximal level (maxLv: the shortest ISI and the biggest workload) in which a subject could perform the task correctly was determined for every subject during rehearsal of the task prior to the experiment. Lowering the level from the maxLv made the task easier. Hemodynamic changes were measured by NIRS over 4 task levels (maxLv-3, maxLv-2, maxLv-1 and maxLv). Results: The hemodynamic changes in the left lateral PFC and bilateral Brodmann area 6 rose significantly with the increase in workload and presented a linear trend. Conclusion: These results suggest that PFC activation may linearly increase with increased workload during a modified RPS task in which successful performance rates of subjects are equalized.