Relationship between loss of pedal sensibility, balance, and falls in patients with peripheral neuropathy
Relationship between loss of pedal sensibility, balance, and falls in patients with peripheral neuropathy
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DOI：
10.1097/01.sap.0000122654.65588.f0
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发表时间：
2004-06-01
影响因子：
1.5
通讯作者：
Dellon, AL
中科院分区：
文献类型：
--
作者：
Ducic, I;Short, KW;Dellon, AL
本研究的目的是描述下肢感觉受损患者人群中平衡和足部感觉之间的关系。这一假说是，感觉障碍的增加与平衡障碍有关。到目前为止，还没有研究神经病人群中平衡丧失与足部敏感度之间的关系的报道。对10名对照受试者和35名与神经病变相关的感觉异常和平衡问题患者进行了评价。MatScan测量系统被用来测量他们站立不动的能力，在他们睁开眼睛和闭上眼睛的情况下保持平衡。人在试图站着不动时移动的程度被定义为“摇摆”，这是为正常和神经病患者记录的。足部的感觉是用压力指定的感觉装置，这是非侵入性和无痛的。测量大脚趾、内侧脚跟和足背的髓部的1点和2点静态触摸阈值。将2分或1分感觉丧失记录为感觉评分，并与对照组进行比较。完成了2组数据的统计分析及其比较。对照组中有55%为女性，神经病患者中有64%为女性，而平均年龄分别为50岁和62岁。64.5%的患者神经病变由糖尿病引起，19.3%由甲状腺功能减退引起，13%由两者联合引起，其余19%的患者病因不明。对照组的平均摇摆显著低于神经病患者（22.9 +/- 9% vs. 189.5 +/-180%，P = 0.006）。同样，正常人和神经病患者的敏感性评分也存在显著差异（31.4 ± 9% vs. 232.8 ± 59%，P
The purpose of this study was to describe the relationship between balance and foot sensibility in a population of patients with impaired lower extremity sensation. The hypothesis was that increasing impairment of sensation correlates with impaired balance. To date, no report has investigated the relationship between loss of balance with the degree of sensibility in the foot in a population with neuropathy. Ten control subjects and 35 patients with sensory abnormalities and balance problems related to a neuropathy were evaluated. The MatScan Measurement System was used to measure their ability to stand still, maintaining their balance with their eyes open and then with their eyes shut. The degree to which the person moves while attempting to stand still is defined as "sway," which was recorded for normal and neuropathy patients. Sensibility of the foot was measured with the Pressure-Specified Sensory Device, which is noninvasive and nonpainful. The 1- and 2-point static touch thresholds are measured for the pulp of the big toe, medial heel, and the dorsum of the foot. Loss of 2- or 1-point sensation was recorded as sensibility score and compared with controls. Statistical analysis of data and their comparisons for the 2 groups was completed. There were 55% females in control and 64% in neuropathy patients, whereas average age was 50 and 62 years, respectively. Neuropathy was the result of diabetes in 64.5%, hypothyroidism in 19.3%, their combination in 13%, and of unknown etiology in the remaining 19% of patients. Controls had significantly lower mean sway than neuropathy patients (22.9 +/- 9% vs. 189.5 +/- 180%, P = 0.006). Likewise, sensibility score for normal and neuropathy patients was also significantly different (31.4 +/- 9% vs. 232.8 +/- 59%, P