TRANSMIGRATION OF LYMPH NODES BY TUMOR CELLS
TRANSMIGRATION OF LYMPH NODES BY TUMOR CELLS
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DOI：
10.1126/science.152.3727.1397
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发表时间：
1966-01-01
期刊：
影响因子：
56.9
通讯作者：
FISHER, ER
中科院分区：
文献类型：
--
作者：
FISHER, B;FISHER, ER
当V2、Brown-Pearce或步行者肿瘤细胞在低压下灌注到腘淋巴结的输入淋巴管中或注射到兔的足垫中时，它们迅速出现在从淋巴结引流的淋巴液中。这一发现表明，淋巴结并不是肿瘤细胞扩散的有效屏障，以前人们认为淋巴结是肿瘤细胞扩散的有效屏障。
When either V2, Brown-Pearce, or Walker tumor cells were perfused at low pressure into the afferent lymphatic of popliteal lymph nodes or were injected into the foot pads of rabbits, they rapidly appeared in lymph draining from the node. This finding indicates that lymph nodes are not the effective barrier to dissemination of tumor cells they had previously been assumed to be.