Chronic Fatigue Syndrome
Chronic Fatigue Syndrome
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DOI：
10.2298/sarh1104256b
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发表时间：
2011-03-01
影响因子：
0.2
通讯作者：
Maric, Daniela
中科院分区：
文献类型：
--
作者：
Brkic, Snezana;Tomic, Slavica;Maric, Daniela
慢性疲劳综合征（CFS）是一种严重的、使人衰弱的疲劳，持续至少6个月，导致职业、个人、社会和教育地位的大幅下降。CFS是一个相对认识不足的临床实体，尽管日常经验表明有许多患者有CFS症状。CFS的发病率和患病率在大多数国家仍然未知;然而，工作人群受影响最大，主要是生殖期的女性患者。虽然CFS在四个世纪前首次被提及，但CFS的神秘的aethiopathogensis仍然困扰着科学家，因为每年仍有数百项关于该主题的研究发表。大约80种不同的病因CFS因素被提及，这些因素可以分为五个基本组：遗传学，免疫学，传染病，内分泌学和神经精神心理学。即使在今天，这种情况也是通过排除器质性和精神疾病的诊断建立的，这需要多学科的方法。由于该综合征经常被误诊和误治，自我药疗在CFS患者中并不少见。此外，这些患者通常会忍受多年的严重疲劳。因此，目前关于CFS有三个优先事项：了解发病机制，诊断测试的发展和创建有效的治疗方案。
Chronic fatigue syndrome (CFS) is defined by a profound, debilitating fatigue, lasting for at least 6 months and resulting in a substantial reduction of occupational, personal, social and educational status. CFS is a relatively poorly recognized clinical entity, although everyday experience shows that there are many patients with CFS symptoms. The incidence and prevalence of CFS remain unknown in most countries; however, the working population is most affected with predominantly female patients in generative period. Although, CFS was first mentioned four centuries ago, mysterious aethiopathogensis of CFS still intrigues scientists as hundreds of studies are still published every year on the subject. About 80 different aetiological CFS factors are mentioned, which can be classified into five basic groups: genetics, immunology, infectious diseases, endocrinology and neuropsychiatry-psychology. Even today the condition is passed established based on the diagnosis by exclusion of organic and psychiatric disorders, which demands u multidisciplinary approach. As the syndrome is often misdiagnosed and mistreated, selfmedication is not uncommon in CFS patients'. In addition, such patients usually suffer for years tolerating severe fatigue. Thus, at the moment there are three priorities regarding CFS; understanding pathogenesis, development of diagnostic tests and creating efficient treatment program.