Bio-PEPA: An Extension of the Process Algebra PEPA for Biochemical Networks

Bio-PEPA: An Extension of the Process Algebra PEPA for Biochemical Networks
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DOI:
10.1016/j.entcs.2007.12.008
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发表时间:
2008-01-20
影响因子:
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通讯作者:
Hillston, Jane
Hillston, Jane
中科院分区:
其他
文献类型:
--
作者:
Ciocchetta, Federica;Hillston, Jane

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在这项工作中,我们介绍了Bio-Pepa,一种用于生化网络建模和分析的进程代数。它是对PEPA的修改,以处理生物模型的一些特征,如化学计量学和通用动力学定律的使用。Bio-Pepa可以被视为生物系统的一种中间的、形式的、组成的表示,可以对其进行不同类型的分析。最后,我们展示了一个模型的表示,关于一个简单的遗传网络,用新的语言。
In this work we introduce Bio-PEPA, a process algebra for the modelling and the analysis of biochemical networks. It is a modification of PEPA to deal with some features of biological models, such as stoichiometry and the use of generic kinetic laws. Bio-PEPA may be seen as an intermediate, formal, compositional representation of biological systems, on which different kinds of analysis can be carried out. Finally, we show a representation of a model, concerning a simple genetic network, in the new language.