Throttles and Dampers: Controlling the Engine of Membrane Fusion
Throttles and Dampers: Controlling the Engine of Membrane Fusion
复制标题
节流阀和阻尼器：控制膜融合引擎
作者：
Leighninger;D. Robert
Thomas H. SA¶llner 囊泡将货物运送到细胞各个部分的目标。本期的新发现表明，两种调节蛋白 Ypt1p（Rab 家族成员）和 Sly1p（Sec1 家族成员）与位于靶标上的 SNARE 蛋白结合。 Rothman 和 SA¶llner 在他们的观点中概述了这两种蛋白质如何充当膜融合过程的节流阀和制动器，从而将细胞成分分配到最终目的地。请参阅本期 Lupashin 和 Waters 的报告
p。 1255.
Thomas H. SA¶llner Vesicles deliver cargo to targets in all parts of the cell. New findings in this issue show that two regulatory proteins, Ypt1p (a Rab-family member) and Sly1p (a Sec1-family member), bind to a SNARE protein located on the target. Rothman and SA¶llner, in their Perspective, outline how these two proteins are likely to act as a throttle and brake for the process of membrane fusion that distributes the cellular constituents to their final destinations. See the report by Lupashin and Waters in this issue on
p. 1255.