White matter connections of high-level visual areas predict cytoarchitecture better than category-selectivity in childhood, but not adulthood.
White matter connections of high-level visual areas predict cytoarchitecture better than category-selectivity in childhood, but not adulthood.
复制标题
在儿童时期，高级视觉区域的白质连接比类别选择性更能预测细胞结构，但在成年期则不然。
DOI：
10.1093/cercor/bhac221
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Grill-Spector,Kalanit
中科院分区：
文献类型：
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作者：
Kubota,Emily;Grotheer,Mareike;Finzi,Dawn;Natu,VaidehiS;Gomez,Jesse;Grill-Spector,Kalanit
颞叶皮层（VTC）由高层次的视觉区域组成，这些视觉区域在个体之间的解剖位置是一致的。这种一致性导致了几个假设的因素，限制职业训练局的职能组织。一个流行的理论是，白色物质连接影响VTC的组织，然而，这种约束的性质是不清楚的。在这里，我们测试两个假设：（1）白色物质束是特定的每一个类别或（2）白色物质束是特定的细胞结构领域的VTC。为了验证这些假设，我们使用扩散磁共振成像来识别白色物质束和功能磁共振成像来识别儿童和成人VTC中的类别选择性区域。我们发现，在儿童时期，白色物质连接与细胞结构有关，而不是与类别选择性有关。然而，在成年期，白色物质连接与细胞结构和类别选择性都有联系。这些结果表明，重新思考的观点，类别选择性区域在VTC有类别特定的白色物质连接的早期发展。相反，这些发现表明，分类刺激处理的神经硬件可能比以前认为的更具有域一般性，特别是在儿童时期。
Ventral temporal cortex (VTC) consists of high-level visual regions that are arranged in consistent anatomical locations across individuals. This consistency has led to several hypotheses about the factors that constrain the functional organization of VTC. A prevailing theory is that white matter connections influence the organization of VTC, however, the nature of this constraint is unclear. Here, we test 2 hypotheses: (1) white matter tracts are specific for each category or (2) white matter tracts are specific to cytoarchitectonic areas of VTC. To test these hypotheses, we used diffusion magnetic resonance imaging to identify white matter tracts and functional magnetic resonance imaging to identify category-selective regions in VTC in children and adults. We find that in childhood, white matter connections are linked to cytoarchitecture rather than category-selectivity. In adulthood, however, white matter connections are linked to both cytoarchitecture and category-selectivity. These results suggest a rethinking of the view that category-selective regions in VTC have category-specific white matter connections early in development. Instead, these findings suggest that the neural hardware underlying the processing of categorical stimuli may be more domain-general than previously thought, particularly in childhood.