The effects of particle shape and size on T2 relaxation in magnetic resonance imaging.
The effects of particle shape and size on T2 relaxation in magnetic resonance imaging.
复制标题
磁共振成像中颗粒形状和尺寸对 T2 弛豫的影响。
DOI：
10.1166/jbn.2014.1870
复制
发表时间：
2014
影响因子：
2.9
通讯作者：
VanKeuren,Edward
中科院分区：
文献类型：
--
作者：
York,JosephN;Albanese,Christopher;Rodriguez,Olga;Le,Yi-Chien;Ackun-Farmmer,Marian;VanKeuren,Edward
超顺磁性氧化铁纳米粒子最近被开发作为磁共振成像的T2造影剂。在这里，我们报告的相位弛豫率，R2，对粒子形状的依赖性。我们表明，球形粒子的弛豫率的大小依赖性可以推广到球形粒子。此外，我们表明，在球形粒子中观察到的弛豫率在一定尺寸以上的饱和不会发生在球形粒子的调查。
Superparamagnetic iron oxide nanoparticles have recently been developed as T 2 contrast agents for magnetic resonance imaging. Here we report the dependence of the phase relaxivity, r2, on the particle shape. We show that the size dependence of the relaxivity for spherical particles can be generalized to spheroidal particles. In addition, we show that the saturation of relaxivity above a certain size observed in spherical particles does not occur in the spheroidal particles investigated.