[Clinical application of FDG-PET for cancer diagnosis].

[Clinical application of FDG-PET for cancer diagnosis].
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FDG-PET在癌症诊断中的临床应用[J].

DOI:
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发表时间:
2003
期刊:
Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica
影响因子:
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通讯作者:
Y. Nakamoto
Y. Nakamoto
中科院分区:
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文献类型:
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作者:
Y. Nakamoto

文献摘要

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使用18F-FDG的正电子发射断层扫描在临床医学中被接受为用于诊断和评估多种癌症的成像工具。自2002年以来,日本已接受这些研究的医疗保险报销。在安装PET设备的机构中,FDG-PET检查的请求数量一直在增加。PET被认为在疾病的重新分期和检测复发方面特别有效。为了正确评价PET图像,重要的是要熟悉FDG的各种生理摄取模式,并警惕假阳性和假阴性结果的可能性。在PET图像中获得的定量值被广泛用于良恶性肿瘤的区分和监测治疗;然而,应该记住,这些值可能受到许多因素的影响。为了弥补PET的空间分辨率较差,已经创建了组合PET/CT扫描仪,并且已经开始其临床应用。预计这种成像工具将是有用的,并对患者管理产生很大影响。
Positron emission tomography using 18F-FDG is accepted in clinical medicine as an imaging tool for the diagnosis and assessment of a large variety of cancers. Medicare reimbursement for these studies has been accepted in Japan since 2002. The number of requests for FDG-PET examinations has been increasing in institutions where a PET device is installed. PET is considered to be especially effective in re-staging and detecting recurrence of disease. In order to evaluate PET images properly, it is important to be familiar with the various physiological uptake patterns of FDG, and also to be alert to the possibility of false-positive and false-negative findings. Quantitative values obtained in PET images are widely used for the differentiation of benign and malignant tumors and for monitoring treatment; however, it should be kept in mind that these values may be influenced by many factors. To complement the poorer spatial resolution of PET, a combined PET/CT scanner has been created and its clinical application has begun. It is expected that this imaging tool will be useful and have a great effect on patient management.