Recent progress, challenges, and opportunities for wearable biochemical sensors for sweat analysis
Recent progress, challenges, and opportunities for wearable biochemical sensors for sweat analysis
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DOI：
10.1016/j.snb.2021.129447
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发表时间：
2021-01-23
影响因子：
8.4
通讯作者：
Ray, Tyler R.
中科院分区：
文献类型：
--
作者：
Ghaffari, Roozbeh;Rogers, John A.;Ray, Tyler R.
汗液是一种很有前途的，但相对尚未开发的生物流体，它含有生物化学信息，可以为人体潜在的动态代谢活动提供广泛的见解。汗液中电解质、代谢物、激素、蛋白质、核酸、微量营养素和外源性物质的丰富组成随着健康、压力和饮食状况的变化而动态变化。新兴的皮肤接口可穿戴传感器提供了强大的功能，可以实时、连续地分析汗液，适用于体育、消费者健康、军事和医疗保健行业。这一观点通过最先进的实施例来研究可穿戴式汗液传感器的快速和持续发展，这些实施例解决了目前限制广泛部署的基本挑战。最后讨论了扩大可穿戴式汗液传感器的整体效用和商业化机会的努力，其中生化传感器技术的进步将是至关重要的。
Sweat is a promising, yet relatively unexplored biofluid containing biochemical information that offers broad insights into the underlying dynamic metabolic activity of the human body. The rich composition of electrolytes, metabolites, hormones, proteins, nucleic acids, micronutrients, and exogenous agents found in sweat dynamically vary in response to the state of health, stress, and diet. Emerging classes of skin-interfaced wearable sensors offer powerful capabilities for the real-time, continuous analysis of sweat produced by the eccrine glands in a manner suitable for use in athletics, consumer wellness, military, and healthcare industries. This perspective examines the rapid and continuous progress of wearable sweat sensors through the most advanced embodiments that address the fundamental challenges currently restricting widespread deployment. It concludes with a discussion of efforts to expand the overall utility of wearable sweat sensors and opportunities for commercialization, in which advances in biochemical sensor technologies will be critically important.