Cigarette Smoking and Breast Cancer Risk in Hispanic and Non-Hispanic White Women: The Breast Cancer Health Disparities Study.
Cigarette Smoking and Breast Cancer Risk in Hispanic and Non-Hispanic White Women: The Breast Cancer Health Disparities Study.
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西班牙裔和非西班牙裔白人女性吸烟与乳腺癌风险：乳腺癌健康差异研究。
DOI：
10.1089/jwh.2015.5502
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Slattery,MarthaL
中科院分区：
文献类型：
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作者：
Connor,AvonneE;Baumgartner,KathyB;Baumgartner,RichardN;Pinkston,ChristinaM;Boone,StephanieD;John,EstherM;Torres-Mejía,Gabriela;Hines,LisaM;Giuliano,AnnaR;Wolff,RogerK;Slattery,MarthaL
目的：很少有流行病学研究包括西班牙裔吸烟和乳腺癌的影响进行评估。我们使用来自乳腺癌健康差异研究（BCHDS）的数据研究了吸烟、种族和乳腺癌风险之间的关系。材料和方法：BCHDS是一个由三个基于人群的病例对照研究组成的联盟，包括美国非西班牙裔白人（NHW）。（1，525例; 1，593对照），美国西班牙裔/美洲原住民（1，265例; 1，495对照）和墨西哥妇女（990例; 1，049对照）。结果：与从不吸烟者相比，墨西哥前吸烟者（OR 1.43，95%CI 1.04-1.96）和吸烟年龄≥31年者（OR 1.95，95%CI 1.13-3.35）患乳腺癌的风险增加。此外，有饮酒史的墨西哥前吸烟者增加了乳腺癌的风险（OR 2.30，95%CI 1.01-5.21）。在绝经前妇女中，每天吸烟≥20支者患乳腺癌的危险性增加（OR 1.61，95%CI 1.07-2.41）。结论：吸烟与乳腺癌的关系可能存在种族差异。
Objective:Few epidemiological studies have included Hispanics with the evaluation of the effects of cigarette smoking and breast cancer. We examined the relationship between cigarette smoking, ethnicity, and breast cancer risk using data from the Breast Cancer Health Disparities Study (BCHDS).Materials and Methods:The BCHDS is a consortium of three population-based case–control studies, including U.S. non-Hispanic whites (NHWs) (1,525 cases; 1,593 controls), U.S. Hispanics/Native Americans (1,265 cases; 1,495 controls), and Mexican women (990 cases; 1,049 controls). Multivariable logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs).Results:Breast cancer risk was elevated among Mexican former smokers (OR 1.43, 95% CI 1.04–1.96) and among those who smoked ≥31 years (OR 1.95, 95% CI 1.13–3.35), compared to never smokers. In addition, Mexican former smokers with a history of alcohol consumption had increased breast cancer risk (OR 2.30, 95% CI 1.01–5.21). Among NHW premenopausal women, breast cancer risk was increased for smoking ≥20 cigarettes per day (OR 1.61, 95% CI 1.07–2.41).Conclusion:Our findings suggest the possibility of ethnic differences with the associations between cigarette smoking and breast cancer risk.