Synthesis of substituted 6-imino-2-piperidinones by Rh-catalyzed [4+2] annulation of 4-alkynals with carbodiimides
Synthesis of substituted 6-imino-2-piperidinones by Rh-catalyzed [4+2] annulation of 4-alkynals with carbodiimides
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DOI：
10.1016/j.tet.2009.06.115
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发表时间：
2009-10-31
期刊：
影响因子：
2.1
通讯作者：
Hojo, Daiki
中科院分区：
文献类型：
--
作者：
Tanaka, Ken;Mimura, Marina;Hojo, Daiki
在室温下，通过阳离子铑(1)/dppp配合物催化各种4-炔醛与碳二亚胺的[4+2]成环反应，合成了取代的6-亚氨基-2-哌啶酮。苯连接的4-炔醛（2-炔基苯甲醛）和碳二亚胺的反应也在室温下进行，得到相应的6-亚氨基-2-哌啶酮。 (C) 2009 Elsevier Ltd. 保留所有权利。
Synthesis of substituted 6-imino-2-piperidinones has been achieved by cationic rhodium(1)/dppp complex-catalyzed [4+2] annulations of various 4-alkynals with carbodiimides at room temperature. The reactions of benzene-linked 4-alkynals (2-alkynylbenzaldehydes) and carbodiimides also proceeded at room temperature, affording the corresponding 6-imino-2-piperidinones. (C) 2009 Elsevier Ltd. All rights reserved.