TENTATIVE MECHANISM FOR INFERIOR PUNCTATE KERATOPATHY

TENTATIVE MECHANISM FOR INFERIOR PUNCTATE KERATOPATHY
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DOI:
10.1016/0002-9394(77)90916-3
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发表时间:
1977-01-01
影响因子:
4.2
通讯作者:
HOLLY, FJ
HOLLY, FJ
中科院分区:
医学1区
文献类型:
--
作者:
ABELSON, MB;HOLLY, FJ

文献摘要

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对10例下点状角膜病变患者和10例正常人的眨眼运动进行了时间推移运动分析。在1min内测定眨眼频率。每个人的时间间隔。我们区分了四种类型的眨眼:完全眨眼、不完全眨眼、抽搐眨眼和强迫眨眼。两组人的平均眨眼频率大致相同:16-17次/分钟。然而,在下部点状角膜病变患者中,完全眨眼的相对比例比正常受试者低得多。眨眼运动受损可能是下角膜上皮点状染色的原因,导致泪膜暴露和不足。出于这个原因,这些患者可能从眨眼训练、泪液替代品或软性隐形眼镜的应用中受益超过常规处方的可的松眼药水。
The blinking motions of 10 patients with inferior punctate keratopathy and 10 normal subjects were analyzed by time-lapse motion pictures. The frequency of blinking was determined during 1 min. intervals for each individual. Four types of blinking were distinguished: complete, incomplete, twitch, and forced blink. The average blinking frequency was about the same for both groups: 16-17 blinks/min. The relative proportion of complete blinks, however, was much lower in patients with inferior punctate keratopathy than in normal subjects. The impaired blinking motion may be responsible for the punctate staining of the inferior corneal epithelium by producing exposure and inadequacies in the tear film. For this reason, these patients may benefit from blink training, application of tear substitutes or soft contact lenses more than from the customary prescription of topical cortisone eyedrops.