Escaping the biofilm in more than one way: desorption, detachment or dispersion.
Escaping the biofilm in more than one way: desorption, detachment or dispersion.
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DOI：
10.1016/j.mib.2016.01.004
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发表时间：
2016-04
影响因子：
5.4
通讯作者：
Sauer K
中科院分区：
文献类型：
--
作者：
Petrova OE;Sauer K
生物膜细菌已经制定了逃逸策略，以避免与生物膜生长相关的压力，对不断变化的环境条件做出反应，并传播到新的地点。越来越多的研究表明，生物膜的细胞释放不同于简单的附着逆转和恢复到浮游生长模式，生物膜的分散涉及特定线索的感知、调节信号转导和随之而来的生理变化。然而，分散只是逃避生物膜生长模式的许多方法之一。本综述旨在通过突出分散细胞特有的调节过程和不同的表型，将这种主动的和受调控的分散过程与被动的解吸和分离过程区分开来。
Biofilm bacteria have developed escape strategies to avoid stresses associated with biofilm growth, respond to changing environmental conditions, and disseminate to new locations. An ever-expanding body of research suggests that cellular release from biofilms is distinct from a simple reversal of attachment and reversion to a planktonic mode of growth, with biofilm dispersion involving sensing of specific cues, regulatory signal transduction, and consequent physiological alterations. However, dispersion is only one of many ways to escape the biofilm mode of growth. The present review is aimed at distinguishing this active and regulated process of dispersion from the passive processes of desorption and detachment by highlighting the regulatory processes and distinct phenotypes specific to dispersed cells.