Evaluation of In Vitro Anti-Inflammatory Activity of Tephrosia purpurea (Seed)
Evaluation of In Vitro Anti-Inflammatory Activity of Tephrosia purpurea (Seed)
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紫毛山毛豆（种子）的体外抗炎活性评价
DOI：
10.5958/2231-5691.2015.00012.x
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
R. Vidhya
中科院分区：
文献类型：
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作者：
A. Anbarasi;R. Vidhya
紫毯种子是一种珍贵的药用灌木和木本植物，在阿育吠陀医学中被重视了几个世纪。对紫荆种子水提液、乙酸乙酯萃取液和己烷萃取液进行植物化学分析，发现三种萃取液均含有多种具有生物活性的植物化学成分。采用HRBC膜稳定法和蛋白变性法，对紫荆不同提取物的抗炎活性进行评价。结果表明，与双氯芬酸钠相比，紫荆水提液在500 μg浓度下具有最高的膜稳定活性（85.6±9.48）和蛋白抑制活性（73.1±8.78）。本研究结果提示植物可能是抗炎治疗的良好天然来源。
Tephrosia purpurea seed is a valuable medicinal shrubby and woody plant which has been valued for centuries in ayurvedic medicine. Phyto-chemical analysis of aqueous, ethyl acetate and hexane T. purpurea seed extracts revealed the presence of various bioactive phytochemical compounds in all three extracts. The study was aimed to evaluate the anti inflammatory activity of different extracts of T. purpurea by HRBC membrane stabilization and protein denaturation method. The result showed aqueous extract of T. purpurea highest membrane stabilizing activity (85.6± 9.48) and protein inhibition activity (73.1± 8.78) at the concentration of 500 μg, when compared to diclofenac sodium. The result obtained from this study suggests that plant is may be a good natural source for anti-inflammatory therapy.