Peak individual alpha frequency qualifies as a stable neurophysiological trait marker in healthy younger and older adults
Peak individual alpha frequency qualifies as a stable neurophysiological trait marker in healthy younger and older adults
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DOI：
10.1111/psyp.12043
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发表时间：
2013-06-01
期刊：
影响因子：
3.7
通讯作者：
Lindenberger, Ulman
中科院分区：
文献类型：
--
作者：
Grandy, Thomas H.;Werkle-Bergner, Markus;Lindenberger, Ulman
人类脑电图的个体阿尔法频率（IAF）反映了大脑的系统特性，具有高度遗传性，并与认知功能相关。关于认知干预对IAF的可改变性，人们知之甚少。我们报告了一项大规模训练研究中的静息脑电图分析，在该研究中，健康的年轻人（20 - 31岁，N = 30）和老年人（65 - 80岁，N = 28）进行了约100次每次1小时的12项认知任务训练。在认知训练干预前后都记录了脑电图。在两个年龄组中，尽管认知表现有很大提高，但IAF（在对照分析中，还有阿尔法波幅）没有变化。由于两个年龄组的组内可靠性和重测稳定性都很高，测量不精确无法解释这些发现。总之，在80岁以下的健康成年人中，IAF高度稳定，不容易仅通过认知干预而改变，因此可作为一种稳定的神经生理特征标记。
The individual alpha frequency (IAF) of the human EEG reflects systemic properties of the brain, is highly heritable, and relates to cognitive functioning. Not much is known about the modifiability of IAF by cognitive interventions. We report analyses of resting EEG from a large-scale training study in which healthy younger (2031 years, N=30) and older (6580 years, N=28) adults practiced 12 cognitive tasks for approximate to 100 1-h sessions. EEG was recorded before and after the cognitive training intervention. In both age groups, IAF (and, in a control analysis, alpha amplitude) did not change, despite large gains in cognitive performance. As within-session reliability and test-retest stability were high for both age groups, imprecise measurements cannot account for the findings. In sum, IAF is highly stable in healthy adults up to 80 years, not easily modifiable by cognitive interventions alone, and thus qualifies as a stable neurophysiological trait marker.