Nickel-Catalyzed Decarbonylation of Acylsilanes
Nickel-Catalyzed Decarbonylation of Acylsilanes
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DOI：
10.1021/acs.joc.0c00772
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发表时间：
2020-06-05
影响因子：
3.6
通讯作者：
Tobisu, Mamoru
中科院分区：
文献类型：
--
作者：
Nakatani, Syun;Ito, Yuri;Tobisu, Mamoru
研究了镍催化的酰基硅烷脱羰反应。与其中甲硅烷基用作离去基团的酰基硅烷的交叉偶联反应形成鲜明对比，甲硅烷基在该脱羰基反应中保留在产物中。尽管解离的CO与镍中心的强结合经常阻碍镍介导的脱羰基反应中的催化剂周转，但该反应可以由带有CO配体的镍络合物催化。
Nickel-catalyzed decarbonylation of acylsilanes is developed. In sharp contrast to cross-coupling reactions of acylsilanes, in which the silyl group serves as a leaving group, the silyl group is retained in the product in this decarbonylation reaction. Although the strong binding of the dissociated CO to the nickel center frequently hinders catalyst turnover in nickel-mediated decarbonylative reactions, this reaction can be catalyzed by nickel complexes bearing a CO ligand.