Comparison of MRI sequences in ideal fiducial maker-based radiotherapy for prostate cancer
Comparison of MRI sequences in ideal fiducial maker-based radiotherapy for prostate cancer
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DOI：
10.1016/j.rpor.2017.10.002
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发表时间：
2017-11-01
影响因子：
1.2
通讯作者：
Matsuo, Masayuki
中科院分区：
文献类型：
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作者：
Tanaka, Osamu;Komeda, Hisao;Matsuo, Masayuki
目的：仅使用CT进行前列腺塑形是困难的。为了克服不确定性，通常执行使用基准标记的CT/MRI配准。然而，使用MRI难以可视化标记本身。本研究的目的是确定最佳的MRI脉冲序列定义的标志物，以及前列腺outline.Materials和方法：共21例连续前列腺癌患者被纳入。CT/MRI检查前放置两个金基准标记。我们使用了以下五个序列：T1加权自旋回波（T1 WI; TR/TE，400-650/8 ms）; T2加权快速自旋回波（T2 WI; 4000/80）; T2*-二维加权梯度回波（T2*2D; 700/18）; T2*-3D加权梯度回波（T2*3D; TR/TE 1/deltaTE，37/14/7.3）;以及对比增强T1加权自旋回波（CE-T1 WI; 400-650/8）。由三名观察员对序列进行定性图像分析。这些观察者对所有图像进行主观评分，评分范围为1-3（1 =不清楚，2=中等，3=可视化良好）。评分越高，表示可视化越好。结果：T2 WI对前列腺的清晰度明显优于其他序列（上级）。T2*2D和T2*3D明显上级其他序列，在基准标记definition.Conclusions：T2*2D和T2*3D是上级其他序列前列腺轮廓和标记识别。因此，我们建议进行初始T2*3D和T2*2D检查。(C)2017年大波兰癌症中心。出版社：Elsevier Sp. z o.o. All rights reserved.
Aim: Prostate contouring using CT alone is difficult. To overcome the uncertainty, CT/MRI registration using a fiducial marker is generally performed. However, visualization of the marker itself can be difficult with MRI. This study aimed to determine the optimal MRI pulse sequence for defining the marker as well as the prostate outline among five sequences.Materials and methods: A total of 21 consecutive patients with prostate cancer were enrolled. Two gold fiducial markers were placed before CT/MRI examination. We used the following five sequences: T1-weighted spin-echo (T1WI; TR/TE, 400-650/8 ms); T2-weighted fast spin-echo (T2WI; 4000/80); T2*-2D-weighted gradient echo (T2*2D; 700/18); T2*-3D-weighted gradient echo (T2*3D; TR/TE1/deltaTE, 37/14/7.3); and contrast-enhanced T1-weighted spin echo (CE-T1WI; 400-650/8). Qualitative image analysis of the sequences was performed by three observers. These observers subjectively scored all images on a scale of 1-3 (1 = unclear, 2=moderate, 3=well visualized). A higher score indicated better visualization. Results: T2WI was significantly superior to the other sequences in terms of prostate definition. T2*2D and T2*3D were strongly superior to the other sequences and were significantly superior in terms of fiducial marker definition.Conclusions: T2*2D and T2*3D are superior to the other sequences for prostate contouring and marker identification. Therefore, we recommend initial T2*3D and T2*2D examinations. (C) 2017 Greater Poland Cancer Centre. Published by Elsevier Sp. z o.o. All rights reserved.