Comparison of 99mTc-MDP SPECT qualitative vs quantitative results in patients with suspected condylar hyperplasia

Comparison of 99mTc-MDP SPECT qualitative vs quantitative results in patients with suspected condylar hyperplasia
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DOI:
10.1016/j.remn.2017.01.003
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发表时间:
2017-07-01
影响因子:
1.2
通讯作者:
Sabogal, A.
Sabogal, A.
中科院分区:
医学4区
文献类型:
--
作者:
Lopez Buitrago, D. F.;Ruiz Bptero, J.;Sabogal, A.

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目的:比较单光子发射计算机断层扫描(SPECT)的定性与定量结果,根据Tc-99 m-MDP的百分比计算(亚甲基二膦酸盐)摄取,在具有髁突增生的推定临床诊断的患者的髁突中。对51例患者的Tc-99 m-MDP SPECT骨显像报告进行了回顾性描述性研究,临床印象与髁突增生有关的面部不对称,由他们的专科医生或颌面外科医生转诊到核医学科进行此类检查。从Tc-99 m-MDP髁突摄取的每一个定量数据,并与定性图像的解释报告的核医学expert.Results:51定性和定量报告结果之间的一致性。总样本包括32名女性(63%)和19名男性(37%)。患者年龄范围为13-45岁(21 +/- 8岁)。根据定性报告,右侧髁突增生19例,左侧髁突增生12例,双侧8例,阴性12例。结论:核医学图像是诊断髁突增生的重要工具,但图像的定性解释不如定量计算可靠。两种报告的一致性较低(39.2%,Kappa = 0.13; P>.2),定量报告的主要局限性是没有记录双侧髁突增生病例。(C)2017 Elsevier Espana,S.L.U. y SEMNIM. All rights reserved.
Objective: To compare qualitative vs quantitative results of Single Photon Emission Computerised Tomography (SPECT), calculated from percentage of Tc-99m-MDP (methylene diphosphonate) uptake, in condyles of patients with a presumptive clinical diagnosis of condylar hyperplasia.Materials and method: A retrospective, descriptive study was conducted on the Tc-99m-MDP SPECT bone scintigraphy reports from 51 patients, with clinical impression of facial asymmetry related to condylar hyperplasia referred by their specialist in orthodontics or maxillofacial surgery, to a nuclear medicine department in order to take this type of test. Quantitative data from Tc-99m-MDP condylar uptake of each were obtained and compared with qualitative image interpretation reported by a nuclear medicine expert.Results: The concordances between the 51 qualitative and quantitative reports results was established. The total sample included 32 women (63%) and 19 men (37%). The patient age range was 13-45 years (21 +/- 8 years). According to qualitative reports, 19 patients were positive for right side condylar hyperplasia, 12 for left side condylar hyperplasia, with 8 bilateral, and 12 negative. The quantitative reports diagnosed 16 positives for right side condylar hyperplasia, 10 for left side condylar hyperplasia, and 25 negatives.Conclusions: Nuclear medicine images are an important diagnostic tool, but the qualitative interpretation of the images is not as reliable as the quantitative calculation. The agreement between the two types of report is low (39.2%, Kappa = 0.13; P>.2).The main limitation of quantitative reports is that they do not register bilateral condylar hyperplasia cases. (C) 2017 Elsevier Espana, S.L.U. y SEMNIM. All rights reserved.