Lung metastasectomy in colorectal cancer: Is this surgery effective in prolonging life?
Lung metastasectomy in colorectal cancer: Is this surgery effective in prolonging life?
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DOI：
10.1111/j.1440-1843.2010.01759.x
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发表时间：
2010-07-01
期刊：
影响因子：
6.9
通讯作者：
Fiorentino, Francesca
中科院分区：
文献类型：
--
作者：
Primrose, John;Treasure, Tom;Fiorentino, Francesca
最常见的情况下，其中肺切除术是执行是复发性结直肠癌。随着癌症团队之间更积极的监测政策，随时可以获得更快的CT扫描以及愿意进行进一步手术以控制复发癌症，肺动脉切除术的实践正在增加。在这场赞成/反对的辩论中，我们探讨了这些问题。双方都认识到，没有随机试验证据可以作为这种做法的基础。不同的意见是，是否有足够的证据，从非常多的病例系列肺和肝切除术的基础上，目前的做法。外科医生的观点是，许多随访研究的证据支持继续这种做法。数学家的观点是，案例选择可以解释几乎所有观察到的结果。
The commonest context in which pulmonary metastasectomy is performed is for recurrent colorectal cancer. With a more active policy of surveillance among cancer teams, ready access to ever faster CT scans and a willingness to perform further surgery to control recurrent cancer, the practice of pulmonary metastasectomy is increasing. In this pro/con debate the issues are explored. It is recognized by both sides that there is no randomized trial evidence on which to base the practice. The difference of opinion is whether there is sufficient evidence from very many case series of both pulmonary and hepatic metastasectomy on which to base current practice. The surgeon's view is that the weight of evidence from many follow-up studies is in favour of continuing this practice. The mathematician's view is that case selection could account for nearly all the observed results.