Detectability of Neural Tracts and Nuclei in the Brainstem Utilizing 3DAC-PROPELLER
Detectability of Neural Tracts and Nuclei in the Brainstem Utilizing 3DAC-PROPELLER
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DOI：
10.1111/jon.12027
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发表时间：
2014-05-01
影响因子：
2.4
通讯作者：
Fujii, Yukihiko
中科院分区：
文献类型：
--
作者：
Nishikawa, Taro;Okamoto, Kouichirou;Fujii, Yukihiko
尽管确定脑干中神经束和神经核的确切解剖位置具有临床重要性，但没有神经影像学研究证实这些结构的可检测性。本研究的目的是评估使用三维各向异性对比度周期性旋转重叠平行线增强重建（3DAC-PROPELLER）成像的结构的可检测性。40名健康志愿者（21名男性，19名女性; 19-53岁，平均23.4岁）参加了本研究。使用3 T-MR系统在脑干的四个水平获得3DAC-PROPELLER轴向图像：下中脑、上下脑桥和延髓。3名专家独立判断是否可以识别每侧的5条束（皮质脊髓束、内侧丘系、内侧纵束、中央被盖和脊髓丘脑束）和10个核（眼神经和滑车神经核、三叉神经脊束、外展神经、面神经、前庭神经、舌下神经、前置神经和孤核、蓝斑、上级和下橄榄）。总共进行了240次评估。在所有相应的评估中识别出5个束和8个核，而蓝斑和上级橄榄分别在3个（1.3%）和16个（6.7%）评估中无法识别。3DAC-PROPELLER是一种非常有价值的成像方法，可用于制定脑干病变的手术策略。
Despite clinical importance of identifying exact anatomical location of neural tracts and nuclei in the brainstem, no neuroimaging studies have validated the detectability of these structures. The aim of this study was to assess the detectability of the structures using three-dimensional anisotropy contrast-periodically rotated overlapping parallel lines with enhanced reconstruction (3DAC-PROPELLER) imaging. Forty healthy volunteers (21 males, 19 females; 19-53 years, average 23.4 years) participated in this study. 3DAC-PROPELLER axial images were obtained with a 3T-MR system at four levels of the brainstem: the lower midbrain, upper and lower pons, and medulla oblongata. Three experts independently judged whether five tracts (corticospinal tract, medial lemniscus, medial longitudinal fasciculus, central tegmental and spinothalamic tracts) and 10 nuclei (oculomotor and trochlear nuclei, spinal trigeminal, abducens, facial, vestibular, hypoglossal, prepositus, and solitary nuclei, locus ceruleus, superior and inferior olives) on each side could be identified. In total, 240 assessments were made. The five tracts and eight nuclei were identified in all the corresponding assessments, whereas the locus ceruleus and superior olive could not be identified in 3 (1.3%) and 16 (6.7%) assessments, respectively. 3DAC-PROPELLER seems extremely valuable imaging method for mapping out surgical strategies for brainstem lesions.