INFLUENCE OF AN ALPHA-AMYLASE INHIBITOR (BAY D 7791) ON BLOOD-GLUCOSE, SERUM-INSULIN AND NEFA IN STARCH LOADING TESTS IN RATS, DOGS AND MAN
INFLUENCE OF AN ALPHA-AMYLASE INHIBITOR (BAY D 7791) ON BLOOD-GLUCOSE, SERUM-INSULIN AND NEFA IN STARCH LOADING TESTS IN RATS, DOGS AND MAN
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DOI：
10.1007/bf01230687
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发表时间：
1973-01-01
期刊：
影响因子：
8.2
通讯作者：
KEUP, U
中科院分区：
文献类型：
--
作者：
PULS, W;KEUP, U
一种从小麦中分离的α-淀粉酶抑制剂被用于涉及大鼠、狗和健康志愿者的实验中。抑制剂可剂量依赖性地降低淀粉负荷引起的高血糖和高胰岛素血症。其抑制作用是特异性的，仅限于α-淀粉酶。在用熟淀粉进行的负荷试验中，对血糖的影响明显减弱。
An a-amylase inhibitor isolated from wheat was used in experiments involving rats, dogs and healthy volunteers. The hyperglycaemia and hyperinsulinaemia resulting from starch loading could be reduced dose dependently by the inhibitor. Its inhibitory effect is specific and limited to α-amylase. In loading tests with cooked starch the effect on blood sugar is markedly diminished.