Biological Sciences: Release of ATP from Rat Motor Nerve Terminals
Biological Sciences: Release of ATP from Rat Motor Nerve Terminals
复制标题
生物科学：大鼠运动神经末梢释放 ATP
DOI：
10.1038/243404a0
复制
发表时间：
1973
期刊：
影响因子：
64.8
通讯作者：
John I. Hubbard
中科院分区：
文献类型：
--
作者：
E. M. Silinsky;E. M. Silinsky;John I. Hubbard;John I. Hubbard
对肾上腺髓质1，2和鱼雷电板的研究表明，ATP在化学递质的储存和释放中发挥了一定的作用。水浴收缩的两栖动物肌肉中含有三磷酸腺苷，但这种三磷酸腺苷被认为是从肌肉中释放出来的。我们提出的证据表明，在哺乳动物神经肌肉制剂的间接刺激下，运动神经末梢释放出三磷酸腺苷。
INVESTIGATION of the adrenal medulla1,2 and the Torpedo electroplax3 suggested that ATP plays some part in the storage and release of chemical transmitters. The fluid bathing contracting amphibian muscle contains ATP, but this ATP was thought to be released from the muscle4. We present here evidence that ATP is released from motor nerve terminals on indirect stimulation of a mammalian nerve-muscle preparation.