Cortical somatosensory evoked potentials in response to hand stimulation.
Cortical somatosensory evoked potentials in response to hand stimulation.
复制标题
皮质体感诱发电位响应手部刺激。
作者：
H. Lueders;Ronald P. Lesser;Joseph F. Hahn;D. Dinner;G. Klem
在6例顽固性癫痫患者中，记录了从长期植入硬膜下电极的体感诱发电位。得出了以下结论：1）初始皮质负-正（N1潜伏期约20 msec，P2潜伏期约24 msec）是典型的初级表面阳性的表现，但N1是由3b区早期水平偶极子的后极产生，P2由1区和2区稍延迟的垂直偶极子的正极产生。2）P2可最准确地定位初级躯体感觉区。3)刺激同侧手在初级体感区没有引起电位。4)在低于感觉阈值的刺激强度下没有观察到皮层电位。弱、强声诱发电位在皮层的分布有显著差异。5)皮层诱发电位的恢复功能呈U型曲线，早期为易化期（10 ~ 30 msec），随后为长时间的亚正常期，峰值约为50 msec。不同皮质部位的恢复曲线不同。
Somatosensory evoked potentials were recorded from chronically implanted subdural electrodes in six patients with intractable seizures. The following conclusions were reached: 1) The initial cortical negativity-positivity (N1 with a latency of about 20 msec and P2 with a latency of about 24 msec) recorded in the postcentral area was an expression of the classical primary surface positivity, but N1 was generated by the posterior pole of an early horizontal dipole in area 3b, and P2 was generated by the positive pole of a slightly delayed vertical dipole in area 1 and 2.2) P2 permitted the most accurate localization of the primary somatosensory area. 3) No potentials were elicited in the primary somatosensory area by stimulation of the ipsilateral hand. 4) No cortical potentials were seen at stimulation intensities below the sensory threshold. The cortical distribution of evoked potentials evoked by weak and strong intensities had significantly different distribution. 5) The recovery function of cortical evoked potentials showed a U-curve with an early period of facilitation (10 to 30 msec) followed by a prolonged period of subnormality which peaked at about 50 msec. The recovery curve at different cortical loci differed.