The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice
The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice
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维生素 K 环氧还原酶 Vkorc1l1 促进小鼠前脂肪细胞分化
DOI：
10.1002/oby.22206
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发表时间：
2018-08-01
期刊：
影响因子：
6.9
通讯作者：
Wu, Xiaohui
中科院分区：
文献类型：
--
作者：
Ding, Yi;Cui, Jing;Wu, Xiaohui
识别参与脂肪发育的新调节因子对于了解肥胖和相关代谢紊乱的分子机制非常重要。本研究旨在通过对维生素K环氧化物还原酶Vkorc1l1突变体的分离和分析，揭示其在脂肪发育中的功能和潜在机制，为肥胖的发生机制提供有价值的见解。
Identification of novel regulators involved in adipose development is important to understand the molecular mechanism underlying obesity and associated metabolic disorders. Through isolation and analysis of a vitamin K epoxide reductase Vkorc1l1 mutant, this study aimed to disclose its function and underlying mechanism in adipose development and to obtain valuable insights regarding the mechanism of obesity.