Methotrexate-induced and Epstein-Barr virus-associated B-cell lymphoma of the spine: MR and PET/CT imaging.

Methotrexate-induced and Epstein-Barr virus-associated B-cell lymphoma of the spine: MR and PET/CT imaging.
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甲氨蝶呤诱导的和 Epstein-Barr 病毒相关的脊柱 B 细胞淋巴瘤:MR 和 PET/CT 成像。

DOI:
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发表时间:
2008
影响因子:
10.6
通讯作者:
A. McCullough
A. McCullough
中科院分区:
医学3区
文献类型:
--
作者:
B. Nguyen;M. Roarke;A. McCullough

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甲氨蝶呤用作治疗类风湿性关节炎和其他结缔组织疾病的疾病缓解剂,可能会抑制免疫系统,并增加免疫缺陷患者群体感染 Epstein-Barr 病毒的高风险。甲氨蝶呤和 Epstein-Barr 病毒的联合作用可能会诱发涉及皮肤、肺、淋巴结和中枢神经系统的淋巴增殖性疾病。作者介绍了一例与甲氨蝶呤相关和 Epstein-Barr 相关的胸椎和椎旁弥漫性大 B 细胞淋巴瘤皮肌炎病例。
Methotrexate, used as a disease-modifying agent in the treatment of rheumatoid arthritis and other connective tissue diseases, may depress the immune system and increase the already high risk of Epstein–Barr virus infection in this immune-challenged patient population. The combined impact of methotrexate and Epstein– Barr virus may induce lymphoproliferative disorders involving skin, lung, nodes and central nervous system. The authors present a case of dermatomyositis with methotrexate-related and Epstein–Barr-associated thoracic spinal and paraspinal diffuse large B-cell lymphoma.
DOI: 10.1093/jnci/djh313
发表时间: 2004-11-17
影响因子: 10.3
作者:
Feng, WH;Cohen, JI;Kenney, SC
通讯作者: Kenney, SC
DOI: 10.1200/jco.1996.14.6.1943
发表时间: 1996-06-01
影响因子: 45.3
作者:
Salloum, E;Cooper, DL;Murren, J
通讯作者: Murren, J